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Progress of the reaction was monitored by HPLC and LC/MS.
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Such non-chimeric revTetR repressor proteins of the present invention constructed from any TetR repressor protein of the TetR(A), TetR(B), TetR(C), TetR(D), TetR(E), TetR(G), TetR(H), TetR(J), and TetR(Z) classes, also, therefore include all members of these classes of TetR proteins and is not to be limited to the specific, exemplary proteins provided in SEQ ID NO: 34, 36, 38, 40, 42, 44, 46, 48, 50 that correspond, respectively to the nine TetR classes provided, and are encoded, respectively by the nucleotide sequence provided in SEQ ID NO: 33, 35, 37, 39, 41, 43, 45, 47, and 49. Electronic orange book: azithromycin for 12 year old drug products with therapeutic equivalence evaluations.
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